Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p217 | Chondrocytes and cartilage | ECTS2016

Effect of combined sex hormone replacement on bone/cartilage turnover in a murine model of osteoarthritis

Oh KwangJun

Background: Estrogens act on estrogen receptors distributed in articular cartilages, synovial membrane, and ligaments, which are thought to be related with degenerative changes. Meanwhile, progesterone is known to have a weak anabolic action on bone formation. This study evaluates the effects of estrogen and progesterone hormone on bone/cartilage turnover in ovariectomized (OVX) rats.Methods: Thirty-five 7-month-old female Sprague–Dawley rats were r...